Tag Archive saliva collector

ByAdminsoft

What are the advantages of using saliva for DNA genetic testing?

What are the advantages of using saliva for DNA genetic testing?

In theory, DNA can be extract from any cell in the body. However, the epithelial cells of the oral mucosa have the characteristics of high metabolism, rapid turnover, and easy shedding,

which can be naturally shedding into saliva. Such cells have a complete human genomic DNA sequence. And related experimental results show that the DNA from saliva and DNA from blood were use for polymerase chain (PCR) reaction,

and the sequencing results of the two were completely consistent.

Generally speaking, there are two sampling methods for genetic testing: one is anticoagulant blood, and the other is saliva collection and testing.

Relevant experiments have shown that the PCR reaction of DNA in blood and epithelial cells extracted from saliva will produce the same sequencing results.

Therefore, whether it is blood or saliva samples, the analysis results should be based on the correct sampling method. ,

There is no difference between the two.

To be precise, it should be the epithelial cells shed in the oral mucosa in the saliva, just like the “Oral swab” of the paternity test sample, do not eat 30 minutes before the sample is collected,

and rinse your mouth with water to prevent foreign bodies in the oral cavity from affecting the timeliness of the sample ,

The epithelial cells of the oral mucosa can naturally fall off into the saliva, and these all contain DNA sequences in the human genome.

Collecting saliva for babies from a young age to a few months is as applicable as a centenarian. One is convenience, but it is painless compare to collecting fingertip blood or venous blood. For the vaccinators who are all “sniffing their teeth”, collecting saliva has the characteristics of easy operation and high safety.

Generally, blood sampling is traumatic sampling, which requires professional or laboratory personnel to collect. Generally, personal collection of samples is not recommend, so it is convenient for customers to collect saliva.

Collecting saliva for testing is a conclusion drawn through practice by thousands of experimental researchers around the world. Facts have proved that saliva samples can guarantee the accuracy of genetic test results,

so there is no need to worry too much about the reliability of saliva samples. Don’t worry about its accuracy!

What are the advantages of using saliva for DNA genetic testing?

ByAdminsoft

What does the saliva collector do to collect saliva?

What does the saliva collector do to collect saliva?

Saliva, commonly known as saliva, is a colorless and thin liquid excreted by the oral cavity and internal glands, with a pH of 6.6 to 7.1. An adult can excrete 1000 to 1500 ml of saliva throughout the day and night.

The composition and function of human saliva: 99% of human saliva is water, follow by substances such as amylase, peroxidase, mucin, phospholipids, phosphoprotein amino acids, potassium, calcium, and magnesium. These substances have the functions of digesting food, antibacterial, and protecting gastric mucosa.

Disadvantages of saliva: Saliva can also spread diseases through the human body with germs.

What can the saliva sampled by the saliva collector be used for?

1. Check for AIDS: In fact, you can find out whether your body is infected with HIV through saliva. The method is quick and easy.

2. Predicting ovulation: Regardless of whether a woman is breastfeeding or not, the glucose content in her saliva is sharply add 5 days before ovulation and 6 days before ovulation. So this can predict the ovulation period, which is helpful for contraception or fertility.

3. Disease prevention and cancer prevention: The mucus protein in saliva can neutralize part of the gastric acid, cause precipitation, attach to the gastric mucosa, form a protective layer, prevent peptic ulcers, and not only kill or inhibit staphylococcus, typhoid bacillus, Escherichia coli, hemolytic streptococcus, etc., and also greatly reduce the toxicity of carcinogens such as aflatoxin, benzopyrene and nitrosamines, and even become harmless substances.

4. Healing wounds: Saliva is rich in nerve growth factors and epidermal growth factors,

which make them accumulate in large amounts at the injured area and repair the wound together with the proliferated capillaries. In addition, the continuous production of collagen fibers can promote hemostasis and wound healing.

The benefits of using saliva samples: Compared with blood samples, saliva samples are easier, more convenient, safer, painless, and non-invasive. The method of collecting saliva samples reduces the risk of contamination and adds the convenience of sampling and inspection. The subjects sampled by themselves. The saliva sample collected by the saliva collector can be use in the saliva preservation fluid to replace blood DNA and is widely use in epidemiological research,

characteristic medicine, drug response monitoring, genetic disease diagnosis, disease probability prediction, and healthy life counseling.

What does the saliva collector do to collect saliva?

ByAdminsoft

What are the characteristics of the saliva collector

What are the characteristics of the saliva collector

Saliva collector is also called saliva sampler, saliva collection device, DNA saliva collection tube. Saliva collection will not cause any discomfort to the sampled person and is easily accepted, so it can greatly expand the sampling range of DNA genetic research.

In fact, the saliva collector consists of a funnel, a sampling tube and a disinfectant. Because the funnel can send saliva directly to the non-toxic stable buffer. In fact, there are clear dividing lines on the surface of the saliva collector. Therefore, the unique funnel design can prevent backflow, and the sampler is very convenient, and it is convenient for the transportation and storage of samples.

The saliva collector can be use to collect saliva samples secrete by the oral cavity, and evenly mix the collect saliva with the saliva preservation fluid, ensuring the integrity of the DNA in the saliva sample and the long-term storage at room temperature. After the sample is extract, it is use for clinical in vitro diagnosis.

Note:

Because DNA is not extract from the saliva itself, but from the exfoliate cells contain in the saliva. Therefore, when collecting saliva samples, please try to use your tongue to scrape the upper and lower jaw as many times as possible, and use your teeth to scrape the tongue a little to ensure the number of exfoliated cells. It is recommend that the first thing that happens in the morning is sampling to ensure the sampling success rate, because eating, drinking, smoking and other behaviors in the past 30 minutes will affect the sampling success rate.

Compared with blood samples, saliva sample acquisition is simpler, more convenient, safe, painless, and non-invasive. The method of collecting saliva samples reduces the risk of contamination, and adds the convenience of sampling and inspection. The subject can take samples by themselves. The saliva samples collect by the saliva collector can be use in the saliva preservation fluid to replace blood DNA and are widely use in epidemiological research, characteristic medicine, drug response monitoring, genetic disease diagnosis, disease probability prediction, and healthy life counseling.

Features of saliva collector:

1. Simple: The product sampling process is simple, fast and easy to operate.

2. Flexibility:

Before blood collection, it was only possible to go to a hospital or a testing institution, but the saliva collector can be easily collected in the laboratory, at home, and in the outpatient clinic.

3. Easy to store:

The sample after sampling is stable, can be stored at room temperature, and is very convenient for transportation.

4. Applicable to a wide range of people:

This method is suitable for all kinds of people, especially for children and patients who do not meet the conditions for blood sampling.

5. Safety:

This method can collect samples non-invasively and reduce the chance of infection.

6. Efficient:

Sample processing is easier to purify automatically, and more DNA/RNA of better quality can be obtained.

What are the characteristics of the saliva collector

ByAdminsoft

Overview of saliva collector

Overview of saliva collector

What is a saliva collector?

The saliva collector can be call not only a saliva sampler, but also a saliva collection device and a DNA saliva collection tube.

The saliva collector is a method of obtaining genetic DNA that is harmless and painless to the human body.

This method not only does not cause any discomfort to the samplers, but it is also easily accepte.

so it can greatly expand the sampling range of DNA genetic research.

First, the most convenient way to collect DNA for genetic testing is to use a saliva collector and then blood.

It is a relatively popular detection method at present.Saliva contains a large number of DNA saliva cells,so it can greatly expand the sampling range of genetic research.

Description of the saliva collector:

Description of the saliva collector:

①、 The saliva collector is composed of a funnel, a sampling tube and a preservation liquid;

②、 The funnel can send saliva directly to the non-toxic stable buffer;

③ 、There are clear graduation lines on the surface of the saliva collector;

④、 The unique funnel design can not only prevent backflow, but also the sampler is very convenient, which is convenient for sample transportation and storage.

⑤、 The saliva collector can not only collect samples at home, but also does not have to go to the hospital to queue up, which is very convenient and time-saving.

⑥、 The saliva collector can not only be used for paternity testing, genetic testing, predict the future development direction of the child, but also predict the disease in advance.

Collection method of saliva collector:

1. Gently spit 2ml of saliva into the saliva collector

2. Pour the preservation solution into the saliva. Close the lid

3. Tumble up and down to mix the saliva and preservation liquid evenly

4. Put the sampling tube in the biosafety bag for inspection

5. Discard the funnel.

Overview of saliva collector