iClean® Saliva Swab Collection Kit

iClean® Saliva Swab Collection Kit is intended for the collection and stabilization of RNA from human Saliva Samples

Ensure the sponge tip does NOT come into contact with anysurface prior to collection.Donor should NOT eat, drink, smoke or chew gum for 30minutes before collecting saliva sample.

HCY Saliva Swab Kit is a self-collection kit that provides thematerials and instructions for collecting human saliva samples.

Precautions:

HCY Saliva Swab Kit is a self-collection kit that provides thematerials and instructions for collecting human saliva sam

ples.

Instructions for sample collection:

1. Open package and remove collector without touching sponge tip. Place sponge as far back in

the mouth as comfortable and rub along the lower gums (see close up image) in a back and forth

motion. Gently rub the gums 10 times. If possible, avoid rubbing the teeth.

2. Gently repeat rubbing motion on the opposite side of the mouth along the lower gums for an

additional 10 times.

3. Hold the tube upright to prevent the liquid inside the tube from spilling. Unscrew the cap from

the collection tube without touching the sponge.

4. Turn the cap upside down, insert the sponge into the tube and close cap tightly.

5. Invert the capped tube and shake vigorously 15 times.

Disease Diagnosis

• Oral Disease Detection: It can be used to collect saliva samples for detecting pathogens such as bacteria, viruses, or fungi in the oral cavity, assisting in the diagnosis of diseases like periodontitis and oral candidiasis. For example, by detecting specific bacterial markers in saliva, it is possible to determine whether there are pathogenic bacteria causing periodontitis, helping doctors formulate targeted treatment plans.
• Systemic Disease Screening: Many systemic diseases are associated with changes in corresponding markers in saliva. For instance, the glucose level in the saliva of diabetic patients may change. Detecting the glucose content in saliva can serve as an auxiliary means for diabetes screening. In addition, for some autoimmune diseases such as Sjögren’s syndrome, detecting components like autoantibodies in saliva is also helpful for disease diagnosis.

Genetic Testing

• Gene Testing: Saliva contains oral mucosal epithelial cells, which carry an individual’s DNA. After obtaining a saliva sample using the iClean® Saliva Swab Collection Kit, gene testing can be carried out to analyze the individual’s gene sequence and determine whether there are pathogenic genes for certain genetic diseases, such as cystic fibrosis and hemophilia. This is of great significance for genetic risk assessment and early prevention among people with a family history of genetic diseases.
• Pharmacogenomics Testing: By detecting the genetic information in saliva, it is also possible to understand an individual’s ability to metabolize certain drugs and their response to them. For example, detecting genetic polymorphisms related to drug metabolism can predict the efficacy and adverse reactions of patients to specific drugs, thereby guiding clinicians to prescribe medications precisely, improving treatment effects, and reducing drug side effects.

Health Management

• Nutritional Assessment: Some components in saliva can reflect an individual’s nutritional status. For example, detecting the levels of nutrients such as vitamin D, zinc, and iron in saliva can help people understand whether their nutrient intake is sufficient. Based on this, they can adjust their dietary structure and reasonably supplement nutrients to maintain good health.
• Lifestyle Assessment: The iClean® Saliva Swab Collection Kit can be used to detect the levels of stress hormones such as cortisol in saliva to evaluate an individual’s stress state. Prolonged exposure to high stress levels can have many adverse effects on physical health, such as a decrease in immunity and an increased risk of cardiovascular diseases. According to the test results, people can take corresponding stress reduction measures, such as exercise, meditation, and adjusting their work rhythm, to improve their quality of life.

Forensic Identification

• Identity Recognition: In crime scenes or forensic investigations, the iClean® Saliva Swab Collection Kit can be used to collect saliva samples for DNA analysis, thus enabling identity recognition. Everyone’s DNA is unique. By comparing with the DNA samples of known individuals, it is possible to determine whether the saliva sample at the scene comes from a specific suspect or victim, providing important clues for solving the case.
• Paternity Testing: Using the DNA in saliva samples for paternity testing is also one of its important applications. By comparing the DNA sequences of parents and children and analyzing the matching situation of genetic loci, it is possible to accurately determine the parent-child relationship, which has important application value in legal disputes, immigration, and other fields.