Nucleic Acid Aerosol Cleaning Kits

A nucleic acid aerosol cleaning kit is a collection of tools or equipment used to clean and remove nucleic acid aerosols from the environment.
It typically contains substances or technologies that adsorb, trap, or degrade nucleic acid aerosols in order to reduce the presence and potential risk of nucleic acid aerosols. These kits may be used in laboratories, medical sites, biosafety containment, etc., to help maintain a clean and safe environment.

The Nucleic Acid Aerosol Cleaning Kit works on the following main principles:
Physical adsorption and filtration principle
High-efficiency filtration materials: Some cleaning kits are equipped with high-efficiency air filters (HEPA), such as microporous filtration membranes made of high-efficiency filtration materials of H14 grade. These filter materials have very small pores, can effectively intercept and adsorb nucleic acid aerosol particles in the air, when the air passes through, the aerosol particles are blocked on the surface of the filter material or inside, so as to realize the purification of air.
Electrostatic adsorption: The air electrostatic disinfection and purification modules in some kits utilize an electrostatic field to electrically charge aerosol particles, which are then adsorbed and captured by electrode plates or filters with an opposite charge. For example, a high-voltage electric field charges passing microorganisms, which are then adsorbed by a dust-collecting electrode plate, achieving the dual effect of killing and trapping, thus removing the microbial components of nucleic acid aerosols.
Chemical oxidative decomposition principle
Strong oxidizing agents: Some cleaning agents or disinfectants in the Nucleic Acid Aerosol Cleaning Kits contain strong oxidizing agents, such as hydrogen peroxide, peroxyacetic acid, etc. These strong oxidizing agents can interact with the microbial components of nucleic acid aerosols. These strong oxidizing agents are capable of reacting chemically with nucleic acid molecules, destroying the structure of the nucleic acids and rendering them inactive and infectious. For example, the oxidative enhancement factor in Novocide air has the effect of strong oxidation in low concentration under the action of metal catalytic ions and stabilizers, which can strongly oxidize aerosol contaminants floating in the air, thus removing nucleic acid contamination.
Metal ion binding: The trace metal ions in some of the products are positively charged, which can easily bind with the base pairs in the nucleic acid fragments, thus destroying the hydrogen bonds between adjacent nitrogen in the base pairs, leading to the deformation of the DNA structure, thus making the nucleic acid lose its biological activity, and thus removing the contamination of nucleic acid.
Photocatalytic principle
UV sterilization: some cleaning kits are equipped with UV lamps, UV has the function of sterilization, its wavelength is 254nm, can quickly destroy the nucleic acid of microorganisms, so that the DNA or RNA in microbial cells are damaged, thus killing microorganisms, achieving the purpose of disinfection, and then reducing the biologically active components in the nucleic acid aerosol.
Photocatalytic reaction: Some photocatalytic materials produce strong oxidizing free radicals, such as hydroxyl radicals, under UV irradiation. These free radicals can react with the organic substances in the nucleic acid aerosol in a redox reaction and decompose them into harmless small molecules such as carbon dioxide and water, thus realizing the purification of the nucleic acid aerosol.
Principle of biological enzyme decomposition
Enzyme-specific degradation: Some cleaning kits contain specific nucleases that can recognize and specifically bind nucleic acid molecules, and then through hydrolysis the nucleic acid molecules are broken down into smaller fragments, which ultimately make them inactive and infectious, thus achieving the effect of removing nucleic acid aerosol pollution.