Nucleic Acid Extraction Kit

Expected purpose

An automatic nucleic acid extractor is a device that can automatically complete the nucleic acid extraction process, and it has a wide range of important applications in multiple fields, which are as follows:

Clinical Diagnosis Field

• Diagnosis of Pathogen Infections: It can quickly and efficiently extract the nucleic acids of viruses (such as the novel coronavirus, hepatitis B virus, human immunodeficiency virus, etc.), bacteria (such as Mycobacterium tuberculosis, Streptococcus pneumoniae, etc.) and fungi (such as Candida albicans, etc.) from various samples of patients (such as blood, sputum, throat swabs, urine, etc.). Through subsequent nucleic acid detection technologies (such as PCR, real-time fluorescence quantitative PCR, etc.), it can achieve early diagnosis, disease monitoring, and treatment effect evaluation of infectious diseases. For example, during the prevention and control of the COVID-19 pandemic, the automatic nucleic acid extractor has greatly improved the efficiency of large-scale nucleic acid testing, providing strong support for timely identification of infected individuals and control of the spread of the epidemic.
• Tumor Detection and Screening: Nucleic acids are extracted from samples such as tissues, blood, pleural effusion, and ascites of tumor patients to detect abnormal conditions such as mutations, methylation, and copy number variations of tumor-related genes. This is helpful for early screening, diagnosis, typing, prognosis evaluation of tumors, as well as the monitoring of treatment efficacy during the treatment process. For example, by detecting gene mutations in circulating tumor DNA (ctDNA), non-invasive or minimally invasive detection of various cancers such as lung cancer and colorectal cancer can be achieved, providing key information for the formulation of personalized treatment plans.
• Diagnosis of Genetic Diseases: Nucleic acids are extracted from samples (such as blood, amniotic fluid cells, etc.) of patients suspected of having genetic diseases, and then gene sequencing, gene chip analysis, etc. are carried out to detect genetic defects such as gene mutations and chromosomal abnormalities, assisting in the diagnosis of genetic diseases, such as thalassemia, cystic fibrosis, hemophilia, etc., and providing important basis for genetic counseling and prenatal diagnosis.

Scientific Research Field

• Gene Expression Analysis: In molecular biology research, the automatic nucleic acid extractor can extract RNA from samples such as cells and tissues, which is used for experiments such as gene expression profiling analysis, real-time fluorescence quantitative PCR, and RNA sequencing to study the expression changes of genes under different physiological states, disease models, drug treatments, and other conditions, and to gain an in-depth understanding of the functions and regulatory mechanisms of genes.
• Genomics Research: It is used to extract genomic DNA, supporting experiments such as whole-genome sequencing, SNP analysis, gene cloning, and gene editing. For example, in projects such as the Human Genome Project, genomic research on animals and plants, and microbial genome analysis, the automatic nucleic acid extractor can efficiently process a large number of samples, providing high-quality nucleic acid samples for genomics research and accelerating the research process of gene mapping, functional annotation, and so on.
• Molecular Evolution Research: Nucleic acids are extracted from samples of different species or different individuals of the same species. By analyzing the differences and similarities of nucleic acid sequences, the evolutionary relationships and genetic diversity of species are studied. The high-throughput and stable characteristics of the automatic nucleic acid extractor make large-scale molecular evolution research possible.

Forensic Identification Field

• Individual Identification: DNA is extracted from biological samples at the crime scene (such as bloodstains, hairs, saliva, semen, tissue fragments, etc.) to construct a DNA fingerprint, which is used for individual identification and screening of criminal suspects. The automatic nucleic acid extractor can quickly process multiple samples, improving the efficiency and accuracy of forensic identification and providing reliable evidence for judicial trials.
• Kinship Identification: In cases involving parent-child relationships, immigration, inheritance of estates, etc., by extracting and analyzing the DNA samples of relevant personnel, the kinship is determined. The automatic nucleic acid extractor can ensure that high-quality DNA can be stably extracted under different sample types and complex conditions, providing strong support for kinship identification.

Food Safety and Quality Control Field

• Pathogen Detection: Nucleic acids of microorganisms (such as Escherichia coli, Salmonella, Staphylococcus aureus, Listeria monocytogenes, etc.) are extracted from food samples (such as meat, vegetables, fruits, dairy products, etc.) to detect pathogenic microorganisms in food, ensuring food safety and preventing the occurrence of foodborne diseases.
• Detection of Genetically Modified Components: DNA is extracted from food, and specific detection methods (such as PCR, gene chips, etc.) are used to detect whether there are specific gene sequences of genetically modified organisms, so as to meet consumers’ demand for the right to know about food. At the same time, it also helps regulatory authorities manage and supervise genetically modified foods.