Detection of Infectious Diseases: It is used to extract the nucleic acids of pathogens (such as bacteria, viruses, fungi, etc.) from samples of patients, such as blood, sputum, pharyngeal swabs, urine, etc., to assist in the diagnosis of infectious diseases, such as the detection of the novel coronavirus, influenza virus, hepatitis B virus, Mycobacterium tuberculosis, etc.
Tumor Diagnosis and Monitoring: Nucleic acids can be extracted from samples such as tissue biopsy samples of tumor patients, circulating tumor cells or cell-free DNA in the blood. It is used to detect changes such as mutations and methylations of tumor-related genes, which is helpful for the early diagnosis, prognosis evaluation and treatment monitoring of tumors.
Genetic Disease Diagnosis: DNA is extracted from samples such as the peripheral blood, amniotic fluid, and chorionic villi of patients to detect gene mutations or chromosomal abnormalities related to genetic diseases, providing a basis for the diagnosis of genetic diseases and prenatal diagnosis, such as the detection of diseases like thalassemia and cystic fibrosis.
Scientific Research
Basic Biological Research: In the fields of cell biology, molecular biology, genetics, etc., it is used to extract DNA and RNA from cell lines and tissue samples to study the expression, regulation, and function of genes. For example, it is used to study the mechanism of the role of genes in the process of cell differentiation and development.
Drug Development: During the drug development process, it is used to extract the nucleic acids of experimental animals or cell models for the screening of drug action targets, evaluation of drug efficacy, research on drug metabolism, etc., helping to develop new drugs and treatment methods.
Microbial Research: For the microbial community in the environment or specific microbial strains, nucleic acids are extracted from environmental samples such as soil, water samples, air, or cultured microbial samples, which are used to study the diversity, evolution, and ecological functions of microorganisms.
Agricultural Field
Crop Genetic Breeding: DNA is extracted from tissues such as the leaves and seeds of crops, which is used for crop variety identification, construction of genetic maps, gene mapping and cloning, etc., assisting in the genetic improvement of crops and the cultivation of new varieties.
Detection of Plant Diseases and Pests: Nucleic acids of pathogens or the nucleic acids of plants themselves are extracted from the tissues of plants infected with diseases and pests. It is used to detect plant pathogenic bacteria, viruses and other pathogens, as well as to study the changes in gene expression of plants under the stress of diseases and pests, providing technical support for the prevention and control of plant diseases and pests.
Detection of Animal Diseases: Nucleic acids are extracted from samples such as the blood, tissues, and feces of farmed animals to detect the nucleic acids of pathogens related to animal diseases, such as avian influenza virus, classical swine fever virus, etc., which is used for the diagnosis and prevention and control of animal diseases and ensures the healthy development of animal husbandry.
Food Safety Detection
Pathogen Detection: Nucleic acid extraction and detection are carried out on pathogenic microorganisms in food, such as Escherichia coli, Salmonella, Listeria monocytogenes, etc., to determine whether the food is contaminated by microorganisms and ensure food safety.
Detection of Genetically Modified Components: DNA is extracted from food samples to detect whether there are genetically modified components in them, providing a technical basis for the labeling and supervision of genetically modified foods and meeting consumers’ needs for food safety and the right to know.
Forensic Identification
Individual Identification: DNA is extracted from biological samples at the crime scene, such as bloodstains, hair, saliva, semen stains, etc. Individual identification and identity verification are carried out through DNA fingerprinting technology, providing important clues and evidence for solving the case.
Kinship Identification: In kinship identifications such as paternity testing and immigration paternity testing, DNA is extracted from samples such as the blood or oral swabs of relevant personnel, and genotyping and comparison are carried out to determine the paternity relationship or other kinship relationships.