The Application of Cell Culture Medium in the Biomedical Field

Cell culture medium is widely used in the biomedical field and is an important support for the development of this field.

In vaccine research, development, and production, cell culture medium plays a key role. Take the influenza vaccine as an example. By culturing cells infected with the influenza virus, such as chicken embryo cells or mammalian cells, in a specific cell culture medium, the virus can proliferate in large quantities. These viruses grown in the medium are processed through a series of purification and inactivation steps and then made into vaccines to prevent the spread of influenza. The quality of the cell culture medium directly affects the yield and quality of the vaccine. A suitable medium can increase the infection efficiency and proliferation rate of the virus, thus increasing the vaccine yield. At the same time, it ensures the safety and effectiveness of the vaccine.

In drug research and development, cell culture medium is an important tool for drug screening and studying the mechanism of drug action. Researchers culture cells in media containing different drugs and observe the effects of the drugs on cell growth, metabolism, and gene expression. In this way, drugs with potential therapeutic effects can be screened out, and the targets and pathways of drug action can be studied in depth. For example, in the research and development of anti – cancer drugs, tumor cells are cultured in media containing different compounds to observe which compounds can inhibit the growth of tumor cells, and then determine whether these compounds have the potential to be developed into anti – cancer drugs.

The field of cell therapy also cannot do without cell culture medium. In CAR – T cell therapy, immune cells need to be collected from patients and then cultured, activated, and genetically edited in vitro using cell culture medium. The medium provides the nutrients and growth factors required for cell growth and proliferation, enabling the immune cells to be amplified in large numbers in vitro and transformed into CAR – T cells with the ability to specifically kill tumor cells. Finally, these cells are reinfused into the patient’s body to achieve the purpose of treating the disease.

Cell culture medium runs through many key links in the biomedical field, such as vaccine research and development, drug development, and cell therapy, making important contributions to the development of human health.