Cell-free DNA blood collection tubes have many advantages:

I. Sample quality
Good cfDNA protection
These blood collection tubes usually contain special protective agents. These protectors prevent the cell-free DNA (cfDNA) in the blood from being degraded by nucleases. Nucleases are naturally present in blood and work by breaking down nucleic acids. If cfDNA is degraded by nucleases in large amounts, the amount of valid cfDNA available for subsequent testing is reduced. The protective agent in the blood collection tube inhibits the activity of nuclease and ensures the integrity of the cfDNA, resulting in more accurate results. For example, in early tumour screening, where intact cfDNA is essential for detecting tumour-associated mutations, the presence of a protective agent increases the likelihood of detecting trace amounts of mutated genes.
High sample stability
Cell-free DNA blood collection tubes maintain sample stability over long periods of time. It ensures the quality of the cfDNA under different storage conditions, such as ambient or defined cryogenic environments. This means that the samples can be stored under the right conditions for a longer period of time, facilitating centralised transport of samples and batch testing. For example, in some large-scale genetic disease screening projects, samples can be transported from various collection points to the central laboratory for testing, during which the samples in the blood collection tubes can remain stable and will not be affected by changes in transport time and environment.
Second, the convenience of testing
Non-invasive or low invasive
Compared with traditional methods of obtaining samples, such as tissue biopsy, cell-free DNA blood collection tubes are a non-invasive or less invasive way of obtaining cfDNA by collecting blood. In prenatal diagnosis, for both the pregnant woman and the foetus, only the peripheral blood of the pregnant woman needs to be drawn to obtain the foetal cfDNA for testing, which avoids the risks of miscarriage and infection that may be associated with invasive procedures such as amniocentesis. In the long-term monitoring of some cancer patients, frequent tissue biopsies will bring more pain and risk to the patients, while blood collection is relatively easy and safe.
Easy to Handle
The use of this blood collection tube is simple and easy to understand. Healthcare professionals only need to follow the routine venipuncture blood collection procedure. No special training or complex equipment is generally required, reducing the difficulty of operation and the possibility of human error during sample collection. In primary healthcare organisations or large-scale screening sites, the simple operation process enables sample collection to be carried out efficiently.
Third, the scope of application
Widely applicable to a variety of disease detection
Cell-free DNA blood collection tubes can be used for a wide range of diseases, including tumours, genetic diseases and infectious diseases. In the field of oncology, it can be used for early screening of cancer, evaluation of treatment effects and metastasis monitoring; in genetic diseases, it can be used for prenatal diagnosis and screening of family genetic diseases; in infectious diseases, it can help to diagnose and monitor diseases through the detection of cfDNA released by pathogens in the blood. This wide range of applicability makes it highly valuable in the field of medical diagnosis.
Suitable for different stages of testing needs
Cell-free DNA blood collection tubes are useful in both the early screening and diagnostic phases of disease, as well as in the monitoring phase of treatment. For example, in the treatment of cancer, from the initial diagnosis and determination of the treatment plan, to the observation of drug efficacy and tumour recurrence during treatment, to the long-term follow-up after treatment, all relevant information can be obtained through cfDNA testing of the blood samples collected using this blood collection tube.