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In addition to tumor detection, cell-free DNA blood collection tubes have the following application scenarios:

Prenatal Testing

  • Chromosome Aneuploidy Screening: By collecting the peripheral blood of pregnant women and using the cell-free DNA in the blood collection tubes for non-invasive prenatal testing, it is possible to accurately detect whether the fetus has chromosome aneuploidy abnormalities such as trisomy 21, trisomy 18, and trisomy 13, providing an important reference for prenatal diagnosis.
  • Diagnosis of Monogenic Genetic Diseases: Analyzing the cell-free DNA in the blood of pregnant women can detect whether the fetus carries the pathogenic genes of monogenic genetic diseases such as thalassemia and hemophilia, which helps to take intervention measures in advance.
  • Fetal Sex Determination: By detecting the sex chromosome information of the fetal cell-free DNA in the peripheral blood of pregnant women, the sex of the fetus can be accurately determined after a certain gestational week, which is of great significance for families with risks related to specific sex-related diseases.

Organ Transplant Monitoring

  • Rejection Reaction Monitoring: After organ transplantation, donor-derived cell-free DNA will appear in the blood of the recipient. By using cell-free DNA blood collection tubes to regularly collect the blood of the recipient and monitoring the changes in the content of donor cell-free DNA, acute rejection reactions can be detected in a timely manner, providing a basis for adjusting the immunosuppressive treatment plan.
  • Graft Injury Assessment: Continuously monitoring the changes in cell-free DNA can be used to assess the functional state and injury degree of the graft, detect graft dysfunction and other problems at an early stage, so that intervention measures can be taken to improve the survival rate of the graft.

Diagnosis of Infectious Diseases

  • Pathogen Detection: When infectious diseases occur, the DNA of pathogens may be released into the blood. By using cell-free DNA blood collection tubes to collect blood, the DNA of pathogens can be detected to assist in the diagnosis of infectious diseases, such as hepatitis B, hepatitis C virus infections, as well as some bacterial and fungal infections.
  • Disease Monitoring and Treatment Efficacy Evaluation: Monitoring the changes in the load of pathogen cell-free DNA in the blood can be used to assess the severity of infectious diseases and the treatment efficacy, guiding clinical medication and the adjustment of treatment plans.

Research on Cardiovascular Diseases

  • Disease Diagnosis and Risk Assessment: Studies have found that there are specific changes in cell-free DNA in the blood of patients with certain cardiovascular diseases such as acute myocardial infarction and heart failure. By collecting blood for cell-free DNA analysis, it helps to assist in the diagnosis of cardiovascular diseases, assess disease risks and prognoses.
  • Research on Pathogenesis: In-depth research on the cell-free DNA in the blood of patients with cardiovascular diseases can help reveal the pathogenesis of the diseases, providing a theoretical basis for the development of new treatment methods and drugs.

Research on Neurological Diseases

  • Diagnosis of Alzheimer’s Disease: There may be characteristic changes related to Alzheimer’s disease in the cell-free DNA in the blood of patients. Through the detection and analysis of these changes, it is expected to provide new methods for the early diagnosis and disease monitoring of Alzheimer’s disease.
  • Assessment of Cerebrovascular Disease Conditions: In patients with cerebrovascular diseases such as cerebral infarction and cerebral hemorrhage, the level and characteristics of cell-free DNA in the blood may also change, which can be used to assess the severity and prognosis of the diseases.

Forensic Identification

  • Individual Identification: The cell-free DNA in the blood contains an individual’s genetic information and can be used for individual identification in forensic identification. For example, in crime scenes, traffic accidents and other scenarios, by analyzing the cell-free DNA in blood samples, the identities of the people involved can be determined.
  • Kinship Identification: By using cell-free DNA blood collection tubes to collect blood samples and analyzing the cell-free DNA in them, kinship identification can be carried out, such as paternity tests and grandparent-grandchild identification, providing evidence for the trial of judicial cases.
Cell-Free DNA Blood Collection Tube
Cell-Free DNA Blood Collection Tube
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