Cell-Free DNA Blood Collection Tube

The cell-free DNA blood collection tube is a special test tube specifically designed for collecting blood samples to obtain cell-free DNA (cfDNA).

Features and Advantages:

Efficiently Protect the Integrity of cfDNA: It contains special preservatives and anticoagulants inside, which can effectively prevent the lysis of cells in the blood and reduce the release of genomic DNA, thus maximizing the preservation of the original state and integrity of cfDNA and ensuring the accuracy and reliability of subsequent analysis and detection.
Optimize Sample Stability: It can maintain the stability of cfDNA within a certain temperature and time range, so that the quality of cfDNA can be well guaranteed during the stages of sample collection, transportation, and storage. This is particularly important for situations where samples need to be transported over long distances or stored for a long time.
Convenience and Compatibility: Its usage method is similar to that of ordinary blood collection tubes, and the operation is relatively simple, making it easy for medical staff to accept and master. Moreover, the collected samples have good compatibility with common cfDNA detection technologies and platforms, and can meet the needs of various downstream experiments and clinical diagnoses.

Specific Applications:

Non-Invasive Prenatal Testing (NIPT): By collecting the peripheral blood of pregnant women and using this blood collection tube to collect the fetal cell-free DNA in it, it can be used to detect fetal chromosomal abnormalities, such as Down syndrome, etc., providing a safe, accurate, and non-invasive testing method for prenatal diagnosis and avoiding the risks of miscarriage, infection, etc. brought by traditional prenatal diagnosis methods (such as amniocentesis and chorionic villus sampling).
Liquid Biopsy for Tumors: It helps to obtain tumor-derived cell-free DNA (ctDNA) from the blood of cancer patients, and then detect biomarkers such as tumor-related gene mutations and gene methylation. It can be used for early diagnosis of tumors, monitoring of treatment efficacy, prediction of recurrence, and guiding targeted therapy, providing crucial support for the precision medicine of cancer patients.
Monitoring of Organ Transplants: After organ transplantation, by regularly collecting the blood samples of the recipients and using this blood collection tube for preservation, analyzing the changes in the level of donor-derived cell-free DNA in it helps to monitor the functional state of the transplanted organ and the situation of rejection reactions, so that the immunosuppressive treatment regimen can be adjusted in a timely manner to improve the success rate of transplantation and the survival rate of the recipients.

Precautions:

Standardize the Collection Process: Blood collection personnel should strictly follow the standard blood collection operation procedures to ensure that the blood collection site is clean and disinfected, the amount of blood collected is accurate, and avoid contamination or hemolysis of blood samples, because these factors may affect the quality of cfDNA and the test results.
Sample Storage Conditions: After collection, the blood collection tubes should be placed upright in an appropriate temperature environment as soon as possible, avoiding violent shaking and long-term exposure to high temperatures or sunlight. If it is necessary to transport samples, appropriate transportation packaging and conditions should be adopted to ensure the stability and security of the samples during transportation.
Expiration Date and Quality Control: Before use, check the expiration date and packaging integrity of the blood collection tubes. Expired or damaged packaging of the blood collection tubes may affect their protective effect on cfDNA, resulting in inaccurate test results. Meanwhile, it is recommended to choose reliable brands with strict quality verification to ensure the reliability of test results and the accuracy of clinical diagnoses.