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In addition to oncology, cell-free DNA collection tubes also have important applications in the following multiple fields:

Prenatal Diagnosis Field

  • Screening for Fetal Chromosomal Abnormalities: It can be used to detect whether the fetus has chromosomal aneuploidy abnormalities, such as Down syndrome, Edwards syndrome, and Patau syndrome. It provides pregnant women with a non-invasive and accurate prenatal screening method, reducing unnecessary invasive examinations.
  • Detection of Fetal Genetic Diseases: For single-gene genetic diseases such as thalassemia and hemophilia, by analyzing the cell-free DNA of the fetus in the pregnant woman’s blood, genetic diagnosis of the fetus can be carried out during pregnancy to determine whether the fetus carries the pathogenic gene, helping families make preparations and decisions in advance.

Organ Transplantation Field

  • Monitoring of Rejection Reactions: By monitoring changes in the content of donor-derived DNA in cell-free DNA, rejection reactions after organ transplantation can be detected early, and the immunosuppressive regimen can be adjusted in a timely manner to improve the survival rate of the transplanted organ and the quality of life of patients.
  • Assessment of Transplanted Organ Injury: Evaluate whether the transplanted organ has conditions such as ischemia-reperfusion injury and infection, and understand the functional status of the graft, providing a basis for clinical treatment.

Cardiovascular Disease Field

  • Diagnosis and Prognosis of Myocardial Infarction: After a myocardial infarction occurs, the level of cell-free DNA in the blood will change, which can be used as an auxiliary indicator for the early diagnosis of myocardial infarction and to assess the degree of myocardial injury and the prognosis of patients.
  • Prediction of Cardiovascular Disease Risk: Detecting relevant markers in cell-free DNA helps predict the risk of cardiovascular diseases and provides a basis for early intervention and prevention in high-risk populations.

Infectious Disease Field

  • Pathogen Detection and Typing: It can detect the cell-free DNA of pathogens in the blood, quickly determine the types of infecting pathogens, such as viruses, bacteria, and fungi, and can also perform genetic typing of pathogens to guide precise anti-infection treatment.
  • Monitoring of Infectious Disease Treatment: During the treatment of infections, by monitoring changes in the content of pathogen DNA in cell-free DNA, the treatment effect can be evaluated, whether the infection is effectively controlled can be determined, and the treatment plan can be adjusted in a timely manner.

Neurodegenerative Disease Field

  • Disease Diagnosis and Monitoring: In neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease, there may be specific methylation changes or gene mutations in the cell-free DNA in the blood, which can be used as potential biomarkers to assist in the diagnosis and monitoring of the disease condition.
  • Drug Research and Development and Efficacy Evaluation: In the research and development of drugs for neurodegenerative diseases, cell-free DNA can be used as one of the indicators for evaluating the efficacy of drugs, helping researchers understand the impact of drugs on disease-related biomarkers and accelerating the drug research and development process.

Forensic Identification Field

  • Individual Identification: The cell-free DNA in the samples collected by cell-free DNA collection tubes can be used for individual identification. In scenarios such as crime scenes and disaster accidents, the identity information can be determined by comparing it with the DNA of known individuals.
  • Kinship Identification: It is used for paternity testing, grandparent-grandchild testing, and other kinship identifications, providing a scientific basis for judicial trials and the resolution of family disputes.
Cell-Free DNA Blood Collection Tube
Cell-Free DNA Blood Collection Tube
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