Nucleic Acid Extraction
The functions and features of the Automatic Nucleic Acid Extractor are as follows:
Function:
Nucleic Acid Extraction: capable of efficiently extracting nucleic acids from a variety of samples (e.g. blood, tissue, saliva, swabs, etc.).
Purification: removes impurities in the sample to obtain high quality nucleic acid.
Features:
High degree of automation: reduces manual operation and improves efficiency and accuracy.
High efficiency and speed: able to complete the nucleic acid extraction process in a short period of time.
High purity and high yield: ensure the extracted nucleic acids have high purity and yield.
Stable: Stable performance and high reproducibility.
Easy to operate: the extraction process can be completed through simple settings and operations.
Wide range of application: applicable to different types of samples and experimental needs.
The automatic nucleic acid extraction instrument has a wide range of applications in the following fields:
Clinical diagnosis
- Pathogen detection: It can quickly extract the nucleic acids of pathogens such as viruses, bacteria, etc. from samples such as patient’s blood, saliva, sputum, tissue, etc., for detecting influenza virus, COVID-19 virus, hepatitis B virus, AIDS virus, etc., to assist doctors in quickly and accurately diagnosing infectious diseases and formulating treatment plans in time.
- Genetic disease diagnosis: Extract nucleic acids from the patient’s cell or tissue samples, and detect gene mutations, chromosomal abnormalities, etc. through the analysis of nucleic acids to assist in the diagnosis of genetic diseases, such as thalassemia, hemophilia, congenital heart disease, etc.
- Tumor marker analysis: Extract nucleic acids from tumor tissues or blood, detect changes in the expression levels of tumor-related genes, etc., to provide a basis for the early diagnosis, typing, prognosis evaluation, and personalized treatment of tumors.
Public health and epidemiological research
- Disease monitoring: During the outbreak of infectious diseases, it can quickly process a large number of clinical samples, accurately and timely detect the nucleic acids of pathogens, help track the transmission path of the disease and monitor the development trend of the epidemic, and provide scientific basis for public health decision-making, for example, it has played an important role in the prevention and control of the H1N1 influenza, hand-foot-mouth disease, etc.
- Pathogen typing: Conduct genetic typing of pathogens to understand the differences in pathogen strains in different regions and at different times, which is helpful for analyzing the source and transmission law of the epidemic, and formulating targeted prevention and control measures.
Drug development
- Drug mechanism research: Extract nucleic acids from tissue or cell samples of cell lines and animal models, analyze the changes in gene expression before and after drug treatment, thereby revealing the target and mechanism of action of the drug, and providing a theoretical basis for new drug development.
- Drug effect evaluation: By detecting the changes in the expression of relevant genes or gene mutations in the patient’s body before and after taking the drug, evaluate the efficacy and safety of the drug, and provide a reference basis for optimizing the clinical medication plan.
Biotechnology research and development
- Gene expression analysis: It can process multiple samples simultaneously, quickly extract high-quality nucleic acids, and is used to study the differences in gene expression in different tissues and cells under different physiological or pathological conditions, which is helpful for revealing the function and regulatory mechanism of genes, and provides important data support for life science research.
- Genomics research: Including genome sequencing, genotyping, genetic mapping, etc., to provide technical support for in-depth understanding of the genetic information, evolutionary relationship, and the relationship between genes and traits of organisms, and promote the rapid development of the genomics field.
- Protein engineering and metabolic engineering: In the research of protein expression and metabolic pathway regulation, nucleic acid extraction instruments can be used to extract nucleic acids in related cells or tissues, analyze the relationship between gene expression and protein synthesis and metabolite levels, and provide basic data for the research and application of protein engineering and metabolic engineering.
Agriculture and plant science
- Genetic improvement: Extract DNA from crop and plant samples to identify and screen genes with excellent traits, such as disease resistance, insect resistance, stress resistance, etc., to provide gene resources for plant genetic breeding and accelerate the breeding process of excellent varieties.
- Variety identification: Through the analysis of plant nucleic acids, determine the variety purity and authenticity of plants, prevent counterfeit and inferior seeds from entering the market, and ensure the quality and safety of agricultural production.
- Disease monitoring: Timely detect the nucleic acids of pathogens in plant samples, monitor the occurrence of crop diseases and pests, and provide a scientific basis for the prevention and control of agricultural diseases and pests, reducing agricultural production losses.
Food safety detection
- Pathogen detection: Detect the nucleic acids of pathogenic microorganisms in food, such as Salmonella, Escherichia coli, Listeria, etc., quickly and accurately determine whether the food is contaminated, and ensure food safety.
- Genetically modified ingredient detection: Detect the genetically modified ingredients in food, determine whether there are genetically modified ingredients and the types and contents of genetically modified ingredients in the food, meet the needs of consumers for food safety and the right to know, and at the same time help regulatory authorities to supervise genetically modified foods.
Environmental monitoring
- Microbial detection: Extract the nucleic acids of microorganisms from environmental samples such as water samples, soil samples, and air samples, analyze the types, quantities, and distribution of microorganisms in the environment, evaluate the quality of the environment and the health of the ecosystem, such as monitoring pollution indicator bacteria in water bodies and beneficial microorganisms in soil.
- Biodiversity research: Through the analysis of the nucleic acids of different organisms in the environment, understand the composition and structure of the biological community, reveal the change law of biodiversity, and provide a scientific basis for environmental protection and ecological restoration.
Forensic identification
- Individual identification: Extract high-quality DNA from biological samples at the crime scene, such as blood, hair, saliva, nails, etc., and compare it with the DNA samples of suspects or in the database to determine the individual identity, and provide strong evidence for the investigation of criminal cases.
- Paternity testing: Through the analysis of the DNA samples of parents and children, determine the parent-child relationship, which has important application value in judicial practice.