Saliva DNA collection cards are specialized tools used for collecting, preserving, and transporting DNA in saliva samples, and they have a wide range of applications in multiple fields. The specific applications are introduced as follows:

In the Field of Medical Diagnosis

• Genetic Testing for Diseases: Many genetic diseases are caused by specific gene mutations. By collecting patients’ saliva and using collection cards to preserve the DNA in it, genetic sequencing and other tests can be carried out to assist in disease diagnosis, such as thalassemia, cystic fibrosis, etc.
• Tumor Detection: The saliva of tumor patients may contain DNA fragments released by tumor cells, namely circulating tumor DNA (ctDNA). Using saliva DNA collection cards to collect samples can detect gene mutations, methylation and other abnormalities in ctDNA, assisting in the early screening, diagnosis, treatment monitoring and prognosis evaluation of tumors.

In the Field of Forensic Science

• Individual Identification and Paternity Testing: In criminal cases or civil disputes, saliva is one of the common sources of biological samples. Saliva DNA collection cards can conveniently collect saliva samples from suspects or parties involved. Through the analysis of the DNA in the samples, individual identity identification or paternity testing can be carried out, providing crucial evidence for case detection and judicial trials.

In the Field of Public Health and Disease Surveillance

• Infectious Disease Surveillance: During the prevention and control of infectious disease epidemics, saliva DNA collection cards can be used to collect saliva samples from suspected patients or close contacts to detect pathogen nucleic acids, assisting in the diagnosis of infectious diseases and epidemic surveillance. For example, during the COVID-19 pandemic, they could be used to collect samples from asymptomatic infected individuals.
• Large-scale Population Screening: When conducting large-scale screening for diseases in specific regions or among specific populations, saliva DNA collection cards have the advantages of being convenient to collect and non-invasive, and are easy to be accepted by the examinees, which can improve the participation rate and efficiency of screening and help in the early detection of diseases and the adoption of corresponding prevention and control measures.

In the Field of Scientific Research

• Genetic Research: In human genetic research, researchers need to collect a large number of DNA samples for genotyping, linkage analysis and other studies to reveal the relationships between genes, diseases and traits. Saliva DNA collection cards provide a convenient and efficient method for large-scale sample collection.
• Drug Development: During the drug development process, it is necessary to analyze the genetic characteristics of patients to predict drug efficacy and adverse reactions. Saliva DNA collection cards can conveniently collect patient samples, providing a DNA source for pharmacogenomics research and facilitating personalized drug development.