The application fields of the cell-free DNA collection tube include the following:

Tumor Early Screening: In the blood of tumor patients, cell-free DNA will be released, which may contain information such as tumor-related gene mutations and methylation. By collecting blood with a cell-free DNA collection tube and detecting the cfDNA, it is helpful to detect the presence of a tumor in the early stage of the tumor when there are no obvious symptoms yet, and realize early intervention.
Tumor Treatment Monitoring: During the tumor treatment process, the patient’s blood is collected regularly, and the changes in the cfDNA are analyzed, such as the disappearance or reduction of gene mutations, and the appearance of new mutations. This can real-time understand the response of the tumor to the treatment and help doctors adjust the treatment plan in time.
Tumor Prognosis Evaluation: The test results of the cfDNA in the blood after treatment can also be used to evaluate the prognosis of tumor patients. If a relatively high level of tumor-related cfDNA can still be detected in the blood after treatment, it indicates a higher risk of tumor recurrence; conversely, the prognosis is relatively better.

Fetal Chromosomal Abnormality Detection: In the peripheral blood of pregnant women, there is cfDNA derived from the fetus. By collecting the blood of pregnant women with a cell-free DNA collection tube and using high-throughput sequencing and other technologies to analyze the cfDNA, it can detect whether the fetus has chromosomal number abnormalities, such as trisomy 21 syndrome, trisomy 18 syndrome, and trisomy 13 syndrome, with the advantages of non-invasive, safe, and high accuracy.
Fetal Monogenic Genetic Disease Diagnosis: For some monogenic genetic diseases with known pathogenic genes, such as thalassemia and hemophilia, prenatal diagnosis can also be carried out by detecting the cfDNA of the fetus in the pregnant woman’s blood, providing accurate diagnostic information for families with genetic risks.

Rejection Monitoring: After organ transplantation, the recipient’s body will contain donor-derived cfDNA. By regularly collecting the blood of the recipient and detecting the level and dynamic changes of the donor cfDNA, early signs of transplant rejection can be detected in time to take timely intervention measures and improve the success rate of transplantation.
Infection Monitoring: Organ transplant patients have a higher risk of infection due to long-term use of immunosuppressants. The blood collected with a cell-free DNA collection tube can be used to detect pathogen infections, such as viruses and bacteria, to detect and treat infections in time and reduce the risk of complications.

Myocardial Injury Assessment: When cardiovascular diseases such as myocardial infarction occur, myocardial cells will release cfDNA into the bloodstream. By detecting the level of cfDNA in the blood and related markers, it can assist in diagnosing the degree and scope of myocardial injury and provide a basis for treatment decisions.
Cardiovascular Disease Risk Prediction: Some genetic and epigenetic information in the cfDNA is related to the risk of cardiovascular disease. By analyzing the cfDNA of a large population of blood, potential disease risk markers can be found for risk prediction and early prevention of cardiovascular diseases.

Disease Diagnosis and Typing: Different types of autoimmune diseases have different pathophysiological mechanisms and cfDNA characteristics. By detecting the blood cfDNA, it can assist in diagnosing autoimmune diseases and perform more accurate typing, providing a basis for personalized treatment.
Disease Activity Monitoring: During the course of autoimmune diseases, the level and changes of the blood cfDNA can reflect the activity of the disease. Regularly detecting the cfDNA can help doctors adjust the treatment plan in time to control the progression of the disease.

Pathogen Detection and Diagnosis: After some pathogens infect the human body, their DNA will be released into the blood to form cfDNA. By collecting blood with a cell-free DNA collection tube and detecting the cfDNA through specific nucleic acid detection technologies, it can realize the early diagnosis and precise treatment of infectious diseases.
Epidemic Monitoring and Prevention and Control: During the outbreak of infectious diseases, the cell-free DNA collection tube can be used for blood collection and detection of a large population, quickly screening out the infected population, understanding the spread range and epidemic trend of the epidemic, and providing strong support for epidemic prevention and control.