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What are the clinical application fields of antibody test kits?

Diagnosis of Infectious Diseases

  • Viral Infections: Such as novel coronavirus, influenza virus, hepatitis B virus, hepatitis C virus, human immunodeficiency virus, etc. By detecting specific antibodies in serum or plasma, it can assist in determining whether there is an infection and the stage of the infection. For example, during the COVID-19 pandemic, antibody testing was used to understand the infection status and immune state of the population.
  • Bacterial Infections: For the diagnosis of infections caused by Treponema pallidum, Mycobacterium tuberculosis, etc. Detecting the corresponding antibodies is helpful for clarifying whether a person has been infected by such bacteria and is of great significance for the diagnosis and condition assessment of diseases.
  • Parasitic Infections: Such as the detection of infections caused by Plasmodium, Toxoplasma gondii, etc. In malaria-endemic areas, antibody test kits can be used to assist in the diagnosis of malaria, especially for some cases with atypical clinical manifestations.

Diagnosis of Autoimmune Diseases

  • Rheumatoid Arthritis: Detecting autoantibodies such as rheumatoid factor and anti-cyclic citrullinated peptide antibody helps in the early diagnosis of rheumatoid arthritis and provides a basis for assessing the disease activity and prognosis.
  • Systemic Lupus Erythematosus: By detecting multiple autoantibodies such as antinuclear antibody, anti-double-stranded DNA antibody, and anti-Smith antibody, doctors can diagnose systemic lupus erythematosus and monitor the disease activity and treatment effect.
  • Autoimmune Thyroid Diseases: Detecting thyroid peroxidase antibody, thyroglobulin antibody, etc. can assist in the diagnosis of autoimmune thyroid diseases such as Hashimoto’s thyroiditis and Graves’ disease.

Evaluation of Immune Function

  • Evaluation of Vaccine Immune Effect: After vaccination, the level of specific antibodies produced in the body is detected to understand the immune effect of the vaccine. For example, hepatitis B surface antibody is detected after hepatitis B vaccination, and specific antibodies against influenza virus are detected after influenza vaccination.
  • Diagnosis of Immunodeficiency Diseases: For patients suspected of having immunodeficiency diseases, detecting the levels of various immunoglobulins and specific antibodies helps in evaluating the immune function state of patients and assists in diagnosing the types and severity of immunodeficiency diseases.

Diagnosis of Allergic Diseases

  • Allergic Diseases: Detecting specific IgE antibodies in serum can identify allergens and assist in the diagnosis of allergic rhinitis, asthma, food allergies and other allergic diseases, providing a basis for desensitization treatment of patients.
  • Drug Allergies: By detecting drug-specific antibodies, it can help determine whether a patient is allergic to a certain drug and avoid serious allergic reactions caused by using the drug again.

Tumor Diagnosis and Monitoring

  • Detection of Tumor Markers: Some tumor markers are essentially tumor-associated antibodies, such as carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), etc. Detecting these antibodies is helpful for the early screening, diagnosis and condition monitoring of tumors.
  • Monitoring of Immunotherapy: During the process of tumor immunotherapy, detecting the level of specific antibodies against tumor antigens in patients can evaluate the effect of immunotherapy and provide a reference for adjusting the treatment plan.
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