Cell-Free DNA Blood Collection Tube

Room temperature preservation: Contains unique anticoagulation and preservation reagents, which

can be stably transported and stored for 7 days or more at room temperature.

Stable storage: It can stabilize nucleated cells and prevent the release of cell genomic DNA from

contaminating target free DNA; inhibit nuclease degradation of free DNA to ensure sample quality.

Personalized design: Double-coded label design, easy to identify, reduce sample processing errors;

clear blood sampling volume identification, easy to observe; there are various material and size for

choice, suitable for different scenarios.

The cell-free DNA blood collection tube is a special blood collection tube designed for collecting and preserving cell-free DNA (cfDNA) in blood. The following is an introduction to it:

Design Principle

• Cell-free DNA typically exists in the blood in a free form, and its content is low and prone to degradation. The cell-free DNA blood collection tube uses special additives and design in the tube to stabilize the cfDNA in the blood, prevent it from being degraded by nucleases, and avoid the contamination of cfDNA by genomic DNA released from broken blood cells, thereby ensuring the quality and integrity of the collected cfDNA.

Application Areas

• Liquid biopsy of tumors: There is tumor-derived cell-free DNA in the blood of tumor patients. By collecting blood and preserving it with a cell-free DNA blood collection tube, tumor-related gene mutations, methylation, etc. can be detected, providing important basis for early diagnosis, treatment monitoring, and prognosis assessment of tumors.
• Non-invasive prenatal testing: There is fetal-derived cell-free DNA in the blood of pregnant women. By collecting the blood of pregnant women with a cell-free DNA blood collection tube, fetal chromosomal abnormalities, gene mutations, etc. can be detected, enabling non-invasive assessment of the health of the fetus, such as screening for common chromosomal diseases such as Down syndrome.
• Organ transplant monitoring: After organ transplantation, the cell-free DNA in the recipient’s blood can reflect the status of the donor organ and immune rejection. By detecting cell-free DNA, early signs of immune rejection can be detected in time, and the immunosuppressive treatment plan can be adjusted to improve the success rate of transplantation.

Advantages and Characteristics

• High sample stability: It can maintain the integrity and stability of cell-free DNA for a long time, ensuring the accuracy of the test results.
• Convenient collection: Similar to traditional blood collection methods, the operation is simple and easy for medical staff to master.
• Good compatibility: The collected samples are compatible with a variety of downstream detection techniques, such as fluorescence quantitative PCR and next-generation sequencing.
• Non-invasive: For patients, collecting blood samples is a relatively non-invasive detection method, reducing the pain and infection risk of patients.

The cell-free DNA blood collection tube provides a reliable and convenient sample collection and preservation method for the detection of cell-free DNA, and has important application value in the fields of clinical diagnosis and research.