The application fields of the cell-free DNA blood collection tube are very extensive, and the following are some of the main application fields:

Early tumor screening: Tumor-derived cell-free DNA exists in the blood of tumor patients. By detecting abnormal situations such as gene mutations and methylation in these cfDNAs, the presence of tumors can be detected at an early stage when the tumors have not yet shown obvious symptoms.
Tumor treatment monitoring: During the course of tumor treatment, the patient’s blood is collected regularly and preserved using a cell-free DNA blood collection tube. By detecting changes in cfDNA, the dynamics of the tumor can be understood in real time, and the treatment effect can be evaluated to provide a basis for adjusting the treatment plan.
Tumor prognosis assessment: The content and characteristics of cfDNA in the blood of patients after treatment are closely related to the risk of tumor recurrence. Through long-term monitoring of cell-free DNA, it is helpful to predict the risk of tumor recurrence and provide guidance for the patient’s subsequent follow-up and management.

Fetal chromosomal anomaly detection: Fetal-derived cell-free DNA is present in the blood of pregnant women. By collecting blood using a cell-free DNA blood collection tube and analyzing the chromosomes of the fetus through high-throughput sequencing and other techniques, chromosomal number abnormalities such as trisomy 21, trisomy 18, and trisomy 13 can be detected.
Fetal single-gene genetic disease detection: For some single-gene genetic diseases with known pathogenic genes, such as thalassemia and cystic fibrosis, by detecting the pathogenic genes carried by the fetus in the mother’s peripheral blood cfDNA, it is possible to diagnose whether the fetus carries the pathogenic genes during the early stages of pregnancy, providing a basis for genetic counseling and decision-making for the family.

Immune rejection monitoring: After organ transplantation, the level of donor-derived cell-free DNA in the recipient’s body is closely related to the occurrence of immune rejection. By regularly collecting the recipient’s blood and preserving it using a cell-free DNA blood collection tube, and detecting the content and dynamic changes of donor cfDNA, early signs of immune rejection can be detected.
Transplant organ damage assessment: The blood samples collected using the cell-free DNA blood collection tube can be used to detect biomarkers related to transplant organ damage. For example, in kidney transplantation, the degree of kidney damage and functional status can be evaluated by detecting cell-free DNA in urine and blood.

Pathogen detection: When an infectious disease occurs, the DNA released by the pathogen can enter the bloodstream and form cell-free DNA. By collecting blood and preserving it using a cell-free DNA blood collection tube, the pathogen DNA can be detected using molecular diagnostic techniques to achieve rapid identification and diagnosis of the infectious pathogen.
Disease progression monitoring: For some chronic infectious diseases, such as hepatitis B and hepatitis C, by long-term monitoring of cell-free DNA in the blood, it is possible to understand the replication of the virus and the progression of the disease, and to provide a basis for adjusting the treatment plan and evaluating the prognosis.

Research on autoimmune diseases: In the blood of patients with autoimmune diseases, the level and characteristics of cell-free DNA may change. By analyzing cell-free DNA, it is helpful to deeply understand the pathogenesis of autoimmune diseases and search for new biomarkers and therapeutic targets.
Forensic identification: The blood samples collected using the cell-free DNA blood collection tube can be used in forensic individual identification and paternity testing. Due to the high stability and specificity of cell-free DNA, it can provide strong evidence in some complex cases, such as the identification of trace blood samples left at the crime scene and paternity disputes.