The specific applications of cell-free DNA blood collection tubes are as follows:

In the Field of Clinical Diagnosis

• Non-invasive Prenatal Testing (NIPT): By collecting peripheral blood from pregnant women and using this type of blood collection tube to stabilize the cell-free fetal DNA (cfDNA) in it, combined with next-generation DNA sequencing technology and bioinformatics analysis, it can detect whether the fetus has chromosomal aneuploidy diseases, such as Down syndrome, Edwards syndrome, and Patau syndrome, avoiding the invasive risks of traditional prenatal diagnosis methods.
• Liquid Biopsy for Tumors: It can be used for early screening, diagnosis, treatment monitoring, and prognosis evaluation of cancer. After the blood sample is collected using the blood collection tube, it can stably preserve circulating tumor DNA (ctDNA), circulating tumor cells (CTC), and other tumor markers in the blood, helping doctors understand the gene mutation status of tumors in real-time, evaluate the treatment effect, monitor minimal residual disease (MRD), and assess the risk of recurrence.
• Diagnosis of Infectious Diseases: In some infectious diseases, the DNA released by pathogens can enter the bloodstream and form cell-free DNA. By collecting blood samples and using cell-free DNA blood collection tubes for preservation, it is helpful for the subsequent detection and analysis of pathogen DNA, assisting in the diagnosis and disease monitoring of infectious diseases.

In the Field of Basic Medical Research

• Cancer Research: It provides high-quality samples for studying gene mutations, epigenetic changes, and other aspects during the occurrence and development of tumors, helping to discover new tumor markers and treatment targets, and further exploring the biological behaviors and molecular mechanisms of tumors.
• Research on Genetic Diseases: It is used to collect blood samples from patients and their relatives for the detection and analysis of genes related to genetic diseases, assisting in studying the genetic patterns of diseases, locating and researching the functions of disease-causing genes.
• Drug Research and Development: In drug clinical trials, it can be used to collect blood samples from patients to monitor changes in gene expression in patients’ bodies and the situation of genes related to drug metabolism during the drug treatment process, providing a basis for evaluating the efficacy and safety of drugs.

In Other Fields

• Forensic Identification: In forensic physical evidence identification, it can be used to collect blood samples and preserve the cell-free DNA in them, providing reliable samples for paternity testing, individual identification, etc., improving the accuracy and reliability of identification.
• Biobank Construction: As an important tool for collecting and preserving blood samples in biobanks, it can stably preserve cell-free DNA in blood for a long time, providing high-quality sample resources for subsequent large-scale population studies and disease resource sharing.